Study on the status and characteristic classification of multiple symptoms in patients with acute exacerbation of chronic obstructive pulmonary disease
YANG Zhenjiao
CUI Miaoling
WANG Zixiu
QIN Lingyu
TAN Guirong
Abstract：Objective:To describe the status of multi-symptoms of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD),and identify their typologies,so as to provide references for targeted intervention.Methods:A total of 202 patients with AECOPD who were hospitalized in a third A hospital from May 2018 to January 2020 were selected as research objects by convenience sampling method.General Information Questionnaire,Modified Medical Research Council(mMRC),Revised Memorial Symptom Assessment Scale and COPD Self-Efficacy Scale were used to investigate the patients.Principal component factor analysis and cluster analysis were used to identify the symptom subgroups based on symptom characteristics and population heterogeneity.Results:A total of 202 patients with AECOPD could be divided into three subgroups:multi-symptom low-grade group(n=103),multi-symptom moderate group(n=60)and multi-symptom high-grade group(n=39).The mMRC score of patients in the high-grade group was significantly higher than that in the other two groups(all P＜0.01).The scores of dyspnea management,physical activity,emotional fluctuation dimension and total self-efficacy were lower than those of low degree group(all P＜0.05).Conclusions:There is population heterogeneity in AECOPD patients with multiple symptoms,which leads to different degrees of distress.The identification of three subgroups of multiple symptoms can provide reference for individualized symptom management.
Keywords：chronic obstructive pulmonary diseaseacute exacerbationsymptom clustersymptom subgroupheterogeneity
Publication Date：2024-02-29
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 614-619 )