Curative effect and perioperative care of advanced cirrhosis patients treated with autologous stem cells transplanta-tion
Liu Feng
Yao Yutong
Li Fuxuan
Abstract：Objective:To summarize the curative effect and perioperative care of advanced cirrhosis patients trea-ted with autologous stem cells transplantation.Methods:A total of 100 advanced cirrhosis patients who had fail-ure conservative therapy by internal medicine were conducted with autologous peripheral blood stem cells trans-plantation for advanced cirrhosis.Preoperative targeted psychological intervention,targeted psychological inter-vention was taken for them,and postoperative rehabilitation guidance was did well,the drug adverse reactions were observed,the vital signs were observed closely and to prevent the complications.Results:One year surviv-al rate was 100% in 100 patients ,the ascites was gradually reduced and disappeared in 52 patients with massive ascites.4 patients underwent upper gastrointestinal bleeding at postoperative 3 months and 3 patients developed with Ⅰ Ⅱ degree of hepatic encephalopathy.After transplantation,the liver synthetic function,liver reserve function and liver elasticity determination were significantly improved (P <0.05 )compared with that before transplantation.Conclusion:Autologous peripheral blood stem cells transplantation could improve the liver func-tion and liver tissue morphology of advanced cirrhosis patients and their quality of life.Perioperative holistic nursing can promote the rehabilitation of patients and improve the curative effect.
Keywords：advanced cirrhosisautologous peripheral blood stem cellsliver functionnursing
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2671-2674 )