Effects of memory updating training combined with cognitive intervention on cancer-related fatigue,fear of recurrence,and chemotherapy adherence in lung cancer patients undergoing chemotherapy
ZHANG Yuanyuan
LI Hong
MA Junzhe
WANG Xiangbing
Abstract：Objective To investigate the effects of memory updating training combined with cognitive intervention on cancer-related fatigue(CRF),fear of recurrence(FoR),and chemotherapy adherence in lung cancer patients undergoing chemotherapy.Methods A prospective study was conducted on 120 lung cancer patients receiving chemotherapy from June 2022 to March 2025.Patients were randomized into control(n=60)and intervention(n=60)groups using number table method.Both groups received cognitive intervention,while the intervention group additionally underwent memory updating training.Outcomes were assessed using the Cancer Fatigue Scale(CFS),Fear of Progression Questionnaire-Short Form(FoP-Q-SF),chemotherapy adherence,and Brief Illness Perception Questionnaire(B-IPQ).Results Repeated-measures ANOVA revealed significant time,group,and interaction effects for physical fatigue,emotional fatigue,cognitive fatigue,total fatigue score,FoP-Q-SF,and B-IPQ(P<0.05).Simple effects analysis demonstrated significant between-group differences at 2 and 4 weeks post-intervention(P<0.05).The intervention group showed significantly higher chemotherapy adherence than controls(P<0.05).Conclusion Memory updating training combined with cognitive intervention significantly improves CRF and FoR in lung cancer patients,with progressive enhancement over time.This integrated cognitive-behavioral approach provides a clinically viable strategy for symptom management.
Keywords：memory updating trainingcognitive interventionlung cancerchemotherapy patientscancer-related fatigue
Publication Date：2026-01-30
Online Publishing Date：2026-01-27(First online date of this platform, not the publication date of the document)
Pages：5( 46-50 )