Effects of treadmill aerobic training combined with butylphthalide on hemorheology and limb function in patients with hemiplegia after ischemic stroke during rehabilitation period
BAO Hualing
WANG Jinglei
MA Binqian
Abstract：Objective To investigate the effect of treadmill aerobic training combined with butylphthalide on hemorheology and limb function in patients with cerebral ischemic stroke(CIS)during rehabilitation.Methods A total of 116 patients with CIS who were treated in Hai an People's Hospital from June 2023 to June 2024 were prospectively selected and divided into contrast group and study group by random number table method,with 58 cases in each group.The contrast group was treated with routine rehabilitation therapy+oral butylphthalide soft capsule,and the study group was treated with treadmill aerobic training on this basis.Both groups were treated continuously for 4 weeks.The efficacy,neurological function[National Institutes of Health Stroke Scale(NIHSS)score],cardiopulmonary function[left ventricular ejection fraction(LVEF),exercise duration(ED),peak oxygen consumption(VO2 max)],hemorheology indexes[plasma viscosity(PV),whole blood viscosity(WBV)],Fugl-Meyer Rating Scale for Lower Extremity(FMA-LE)score,modified Barthel index(MBI)score,Berg Balance Scale(BBS)score.Results After treatment,the total effective rate of the study group was 94.83%,which was higher than that of the contrast group(79.31%)(χ2=5.352,P<0.05).After the treatment,the levels of the NIHSS score,WBV,and PV in the observation group were all lower than those in the control group(t=11.401,8.177,7.452,P<0.05).Meanwhile,the LVEF,ED,VO2max,FMA-LE score,BBS score,and MBI score in the observation group were all higher than those in the control group(t=3.930,4.926,3.617,5.383,6.709,4.377,P<0.05).Conclusion The use of treadmill aerobic training combined with butylphthalide in CIS patients has a significant effect,which can effectively improve their cardiopulmonary function and hemorheology,improve neurological function,lower limb motor ability and daily living ability.
Keywords：bicycle aerobic trainingbutylphthalideischemic strokehemorheologylimb function
Publication Date：2025-10-31
Online Publishing Date：2025-11-17(First online date of this platform, not the publication date of the document)
Pages：4( 855-858 )