Observation of the effect of using vibratory expiratory positive pressure airway clearance during acute exacerbation of chronic obstructive pulmonary disease
YUAN Yan
ZHAO Mingming
LI Rongfei
DUANMU Yirong
LIN Ling
CAO Luchan
Abstract：Objective To compare the application effects of vibratory positive end expiratory pressure(oscillatory positive expiratory pressure,OPEP)and active circulation breathing technique(active cycle of breathing techniques,ACBT)in airway clearance of patients with acute exacerbation of chronic obstructive pulmonary disease(chronic obstructive pulmonary disease,COPD).Methods 120 COPD patients admitted between January and December 2024 were included in the study.Randomly divided into two groups,with 60 cases in the ACBT group and 60 cases in the OPEP group.Both groups underwent continuous airway clearance with ACBT and OPEP for 7 days.Compare the daily sputum volume and sputum viscosity between two groups of patients.The Modified Dyspnea Index(modified Medical Research Council scale,mMRC)was used to evaluate the respiratory changes of patients at the time of enrollment and on the 3rd and 7th day of treatment,and to compare the adverse reactions and length of hospital stay between the two groups.Results On days 2-5,the sputum output of the OPEP group was higher than that of the ACBT group,with P values<0.05.On days 6-7,there was no statistically significant difference in sputum output between the two groups(P>0.05).On the 3rd and 7th day,although the proportion of grade I in the OPEP group was higher than that in the ACBT group,there was no statistically significant difference between the groups(P>0.05).There was no statistically significant difference in mMRC scores between the two groups at the time of enrollment and on day 7.On day 3,the OPEP group had lower scores than the ACBT group(t=2.814,P=0.006).The average hospitalization time in the ACBT group was(9.12±2.06)days,while in the OPEP group it was(8.53±1.89)days,with a statistically significant difference(t=1.614,P=0.109).There was no statistically significant difference in adverse reactions between the two groups(P>0.05).Conclusion The use of vibratory positive expiratory pressure for airway clearance in AECOPD patients can more effectively promote earlier sputum clearance,alleviate earlier clinical symptoms,and is safe and easy to learn.It can be used as an adjuvant treatment for patients with acute exacerbation of chronic obstructive pulmonary disease.
Keywords：chronic obstructive pulmonary diseaseoscillatory positive expiratory pressureactive circulation breathingairway clearance
Publication Date：2025-10-31
Online Publishing Date：2025-11-17(First online date of this platform, not the publication date of the document)
Pages：4( 773-776 )