The value of individualized hemodialysis management in preventing hypoglycemia during dialysis in diabetic patients

doi:10.3969/j.issn.1674-3245.2025.01.037

Abstract：Objective: To explore the value of individualized hemodialysis management in preventing hypoglycemia during dialysis in diabetic patients. Methods: A total of 100 diabetic patients who received hemodialysis treatment at the Fourth Affiliated Hospital of Nanjing Medical University from January 2020 to December 2022 were selected and randomly divided into an observation group (individualized hemodialysis management, 50 cases) and a control group (routine hemodialysis treatment, 50 cases). The blood glucose levels, incidence of hypoglycemia, and complication rates during hemodialysis were compared between the two groups. Additionally, the levels of urea nitrogen (BUN), serum creatinine (Scr), albumin (ALB), and hemoglobin (Hb) before and after hemodialysis intervention were compared. Results: The blood glucose levels at 1, 2, and 3 hours during hemodialysis and immediately after hemodialysis were significantly lower than those before hemodialysis in both groups (t=6.411, 7.160, 7.058, 6.983, P<0.05), but there was no significant difference between the two groups (P>0.05). During hemodialysis, the total incidence of hypoglycemia in the observation group was 1.99%, which was significantly lower than that in the control group (4.99%) (χ2=42.397, P<0.05). After intervention, the BUN (5.89±1.41 mmol/L) and Scr (217.34±25.52 μmol/L) levels in the observation group were significantly lower than those before intervention (25.57±3.68 mmol/L, 912.12±54.66 μmol/L) and those in the control group (9.13±1.52 mmol/L, 310.15±30.46 μmol/L). The ALB (33.96±6.71 g/L) and Hb (12.03±2.67 g/L) levels in the observation group were significantly higher than those before intervention (27.88±4.36 g/L, 9.54±3.13 g/L) and those in the control group (29.24±7.12 g/L, 10.34±2.99 g/L) (P<0.05). The total incidence of complications in the observation group was lower than that in the control group, with statistically significant differences (t=11.050, 16.515, 3.411, 3.981, P<0.05). Conclusion: Individualized hemodialysis management can prevent hypoglycemia in diabetic patients during dialysis.