Efficacy of early pulmonary rehabilitation intervention for elderly patients with type 2 diabetes mellitus combined with stroke-associated pneumonia
Yu Kaina
Gao Naifen
Fan Sufang
Di Yiyao
Che Conglu
Xu Shenghui
Abstract：Objective To explore the efficacy of early pulmonary rehabilitation intervention in treating elder patients with T2DM combined with SAP.Methods 110 cases of elderly patients with T2DM combined with SAP admitted to the Second Hospital of Shijiazhuang City from March 2021 to October 2022 were selected and divided into observation group and control group,with each group 55 cases.Control group received routine treatment with liraglutide and piperacillin sodium tazobactam sodium,and observation group received early pulmonary rehabilitation intervention on this basis.Both groups were treated for 2 weeks.Compared the lung function indexes(FEV1,FVC,FEV1/FVC),CPIS score,serum inflammatory factor levels[serum PCT,hs-CRP,TNF-α],efficacy and adverse reactions.Results The total clinical effective rate of observation group(92.73%)was higher than that of control group(78.18%)(χ2=4.681,P<0.05).After,FEV1,FVC and FEV1/FVC levels in observation group were higher than those in control group[(3.78±0.96)L vs.(3.24±0.92)L,(5.27±1.42)L vs.(4.21±1.46)L,(78.29±12.48)vs.(71.36±11.45)],with statistically significant differences(t=3.012,3.860,3.035,P<0.05).Serum PCT,hs-CRP,and TNF-α levels were lower in observation group than in control group[(0.92±0.25)μg/L vs.(1.13±0.37)μg/L,(12.86±3.14)mg/L vs.(15.41±3.58)mg/L,(2.84±0.78)μg/L vs.(3.42±0.93)μg/L],and the differences were statistically significant(t=3.488,3.971,3.544,P<0.05).The total incidence of adverse reactions in patients in the observation group compared with the control group(9.09%vs.12.73%),the difference was not statistically significant(χ2=0.374,P>0.05).Conclusion Early pulmonary rehabilitation intervention has shown good therapeutic effects in elderly T2DM patients with SAP,promoting the recovery of lung function,reducing serum inflammatory factor levels,and owning good safety.It can provide new ideas for clinical treatment and intervention measures.
Keywords：Early pulmonary rehabilitation interventionType 2 diabetes mellitusStroke-associated pneumoniaSerum inflammatory factor
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 765-768 )