Discussion on the duration of fasting in patients with acute non varicose upper gastrointestinal bleeding

Liu Yehong; Shen Zhao

doi:10.3969/j.issn.1674-3245.2024.03.015

Abstract：Objective To observe the effect of early oral feeding after hemostasis on clinical outcomes such as rebleeding in patients with acute non variceal upper gastrointestinal bleeding(ANVUGIB).Methods A total of 120 hospitalized patients with ANVUGIB from February 2020 to August 2023 were randomly divided into two groups.The early feeding group(n=60)resumed oral intake within 12 hours after endoscopic examination and hemostasis treatment,without experiencing frequent vomiting and maintaining stable hemodynamics.The conventional fasting group(n=60)fasted with water for 72 hours after hemostasis and received intravenous nutrition.Hospitalization time,rebleeding rate,and hospital mortality rate were compared between the two groups.Compare the levels of blood potassium(K+),blood sodium(Na+),hemoglobin(Hb),and albumin(Alb)between the two groups before and after treatment for 3 days.Results There was no statistically significant difference in age,gender,Forrest grading,bleeding site,and whether blood transfusion was performed between the two groups(P>0.05).There was no statistically significant difference in Hb,Alb,K+,Na+between the two groups before and 3 days after treatment(P>0.05).The average hospitalization time of the early eating group was(4.92±2.07)days,which was lower than the(6.15±2.83)days of the conventional fasting group.There was a statistically significant difference between the groups(t=2.717,P=0.008).There was no statistically significant difference in rebleeding rate and hospital mortality rate between the two groups(P>0.05).Conclusion For patients with acute non-variceal upper gastrointestinal bleeding,oral feeding within 12 hours after endoscopic examination and hemostasis treatment shortenes hospitalization time without increasing the risk of recurrent bleeding and mortality.