The effect of double tube and double transfusion on hemodynamics and blood gas in patients with acute upper gastrointestinal hemorrhage
Li Changfeng
Lu Shengfang
Abstract：Objective This study explored the clinical effect of double tube and double transfusion in the treatment of patients with acute upper gastrointestinal bleeding. Methods 120 patients with acute upper gastrointestinal bleeding admitted to our hospital from 2015.3 to 2017.3 were selected. Patients were randomly divided into two groups:the experimental group(the double tube double transfusion method was added to the blood volume) and the control group(routine blood volume supplement) in 60 cases. The HR,MAP,SpO2,PaO2,PaCO2,and pH values were compared between the two groups before and after treatment. The cure rate and mortality of the two groups were compared. Results The volume of blood transfusion in the experimental group was 685.2+85 ml/h, the blood transfusion amount in the control group was 456.8 + 64 ml/h,and the volume of blood transfusion at unit time in the test group was higher than that of the control group (P＜0.05). Before treatment,the difference in HR,MAP,SBP values between the two groups was not statistically significant (P＞0.05);after 1 hour of treatment, 2 hours of treatment, and 4 hours of treatment, the HR of the experimental group was lower than that of the control group(P ＜ 0.05), and the MAP, SBP value was high. In the control group (P ＜ 0.05);Before treatment,there was no statistically significant difference in SpO2,PaO2,PaCO2,pH values between the two groups (P＞0.05). After 1 hour of treatment, 2 hours of treatment, and 4 hours of treatment, the PaCO2values of the experimental group and the control group were not statistically different(P＞0.05). SpO2, PaO2, pH value were higher than the control group (P ＜ 0.05);The cure rate of the experimental group was 95.00% compared with 90.00% of the control group, and the difference was not statistically significant (P＞0.05). There was no significant difference in the incidence of adverse reactions in blood transfusion between the two groups (P ＞ 0.05). Conclusion In the treatment of acute upper gastrointestinal bleeding, double tube and double transfusion can quickly correct the circulatory dysfunction and improve the blood gas level of the patients, but the decrease of clinical mortality is not obvious in this study.
Keywords：Double tube and double transfusionAcute upper gastrointestinal hemorrhageHemodynamicsBlood gas
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 312-314 )