The incidence of frailty and risk factors in people with COPD

doi:10.3969/.issn.1674-3245.2018.03.014

Abstract：Objective To investigate the incidence and risk factors of frailty in patients with chronic obstructive pulmonary disease(COPD),and the impact of frailty on activities of daily living(ADL)in COPD patients.Methods A cross-sectional study was carried out in patients including outpatient of respiratory department and inpatient of department of cadre ward from General Hospital of Lanzhou Military Region of PLA.We used Fried frailty criteria to assess the incidence of frailty in patients with COPD.We also used multiple logistic regression analysis to find out the risk factors of frailty and the impact of frailty on ADL.Results A total of 378 COPD patients were included in this study including 231 males and 147 females.The total incidence of frailty was 44.7％(169 patients,97 males and 72 females),incidence of frailty was 42％for male and 49％for female.Risk factor for frailty included age(per year)(OR 1.02,95％CI 1.01～1.05),number of co-morbidities(＞1)(OR 2.13,95％CI 1.41～4.05),history of diabetes(OR 3.18,95％CI 1.32～8.27)and respiratory symptom(shortness of breath on stairs/inclines)(OR 1.94,95％CI 1.51～3.85).COPD patients with frailty had high risk for ADL [eating(OR 1.64,95％CI 1.21～2.44),dressing(OR 1.89,95％CI 1.32～2.92),cooking(OR 2.21,95％CI 1.47～3.23)and doing housework(OR 2.33,95％CI 1.51～3.47)].Conclusion The incidence of frailty was high in COPD patients,many factors contribut to the occurrence of frailty in COPD patients and COPD patients has high risk of difficulty in ADL.