Study on the relationship between the changes of physiological indexes of red blood cells and coronary artery disease in the native of high altitude area
Abstract：Objective To study the relationship between the changes of physiological indexes of red blood cells and the coronary artery disease(CAD)in the native of high altitude area.Methods From January 2014 to december 2016,618 patients with coronary heart disease(CHD)admitted to our hospital because of chest pain and suspected coronary artery disease were as CHD group. And 621 patients with normal coronary angiography were as control group. Check and record clinical data for statistical analysis. Results Gender,smoking history,hypertension history,diabetes history were all different in two groups(P< 0.05). And D-Dimer,WBC,HCT,RDW,TBIL,IBIL,LDL-C,HDL-C were statistically significant different(P<0.05);Logistic regression analysis showed that male,smoking,diabetes,hypertension,age,D-Dimer,RDW,LDL-C were risk factors for coronary heart disease(P <0.05);TBIL,HDL-C were protective factors for coronary heart disease(P<0.05). CHD group were divided into low altitude group, middle altitude group,high altitude group according to altitude cut-off point of 2000 meters and 3000 meters. There were siginficant difference on percentage of male,age proportion and TBIL levels among three groups(P< 0.05). Conclusion Male,age,smoking, diabetes,hypertension,D-Dimer,RDW and LDL-C are independent risk factors of coronary heart disease in native plateau population. TBIL and HDL-C are protective factors for coronary heart disease,with the increase of residence altitude,patients with coronary heart disease will show a trend of young age.
Keywords：Plateau areaCoronary heart diseaseRed blood cellHematocritRed blood cell distribution width
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 28-32 )