Efficacy and safety of ticagrelor in elderly with acute myocardial infarction
Fu Wenke
Liu Yuan
Han Baoshi
Abstract：Objective To evaluate the efficacy and safety of ticagrelor in elderly people with acute myocardial infarction. Methods In total, 180 elderly people 60 years and older with acute myocardial infarction were included; the participants were assigned randomly and evenly to take ticagrelor or clopidogrel. The treatment course lasted for 12 months. Results Median age was 72 (61-84) years,and 98 men were included. The incidence of recurrent myocardial infarction and cardiovascular death were significantly lower in the elderly participants taking ticagrelor compared to those taking clopidogrel (all P < 0.05). There was no difference in the incidence of bleeding between the two groups (P > 0.05). Conclusion The incidence of recurrent myocardial infarction and cardiovascular death were lower and the incidence of bleeding was similar in elderly people taking ticagrelor compared to those taking clopidogrel,showing the efficacy and safety of ticagrelor in elderly people with acute myocardial infarction.
Keywords：Acute myocardial infarctionTicagrelorClopidogrel
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 104-106 )