The clinical risk factors of prolonged mechanical ventilationand the long-term prognosis in elderly adults after high-risk surgery
Abstract：Objective To analyze the clinical risk factors and long-term prognosis of prolonged mechanical ventilation in elderly adults after high-risk surgery. Methods The patients aged ≥ 65 years who had high-risk surgery from January 2006 to January 2016 in the South Building of Chinese PLA General Hospital were included. The clinical risk factors and outcomes of prolonged mechanical ventilation were assessed by logistic regression. Results We identified 2886 patients aged ≥ 65 years who had high-risk surgery,6.3% received prolonged mechanical ventilation during the hospitalization.Patients received prolonged mechanical ventilation had higher incidence of coronary heart disease,heart failure,hypertension,dementia,and chronic obstructive pulmonary disease than patients who did not have prolonged ventilation. Older age ,higher APACHEⅡscore,chronic obstructive pulmonary disease,hypertension,andemergent surgery status were the clinical risk factors.The survivors who received prolonged mechanical ventilation had a higher 1-year mortality rate than patients who did not have prolonged ventilation.Patients who received prolonged ventilation had a substantially increased 1 -year mortality and higher incidence ofre -tracheal intubation and unconsciousness≥24 hours than the control group. Conclusion Greater knowledge of the clinical risk factors and clinical outcomes of old patientswho received prolonged mechanical ventilation was helpful to identify the high risk patients and toimprove the prognosis of these patients.
Keywords：Prolonged mechanical ventilationRisk factorsClinical prognosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 24-27 )