Study of correlation between left ventricle myocardial three-dimensional stain and complications of microangiopathy in type 2 diabetes patients
Abstract：Objective The aim of this study was to assess the relation between diabetic microvascular complications and left ventricle myocardial three-dimensional stain in type 2 diabetes patients. Methods Forty-five asymptomatic patients with type 2 diabetes mellitus (2DM) and Forty-one age-matched healthy control subjects underwent 3D echocardiography. Presence of proliferative retinopathy,nephropathy,and cardiac autonomic neuropathy were defined as diabetic microvascular complications. Echocardiogram images of the short axis of the left ventricle and apical long axis were obtained. The three-dimensional speckle tracking echocardiography was used to analyze the left ventricular global longitudinal strain (GLS),globalendocardial area strain (GAS),global circumferential strain (GCS) and the global radial strain (GRS). Results LVEF,LVEDV,LVESV,and GRS were similar between controls and DM patients (P>0.05). However,compared to controls,GLS,GCS and GAS were significantly reduced in patients with DM patients (P < 0.05). In DM patients,GLS was related to microangiopathy burden score (r = 0.610,P < 0.01). Conclusion Microvascular complications in diabetic patients are significantly associated with subclinical left ventricular dysfunction that is characterized by impaired left ventricular longitudinal function.
Keywords：Left ventricle myocardial three-dimensional stainComplications of microangiopathyType 2 diabetes patients
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 21-23 )