The associations of plasma Apo CIII with coronary heart disease and lipids and the effect of statin treatment on them
Abstract：Objective To study the associations of Apo CIII with coronary heart disease (CHD) and plasma lipids and the effect of statin treatment on them. Methods A total of 143 patients were enrolled,included 80 non-CHD patients and 63 CHD patients,and CHD patients received statin treatment and were followed up. Clinical information of all the patients was recorded,and fasting vein blood was collected to measure lipids and Apo CIII level. The associations of Apo CIII with CHD and lipids and the effect of statin treatment on them were analyzed by statistic method. Results The Apo CIII level of CHD was lower than non-CHD,and it was elevated significantly after statin treatment (P<0.05). The association of Apo CIII with triglyceride was significant in non-CHD (P<0.05). The associations of Apo CIII with total cholesterol and triglyceride were significant in CHD patients (P<0.05),and the associations between them were not affected by statin. The association of Apo CIII with low density lipoprotein cholesterol was significant in CHD patients after statin treatment only. Conclusion There are some associations of Apo CIII with CHD and lipids parameters,and it is also affected by statin treatment in some extent.
Keywords：Coronary heart diseaseApolipoprotein CIIIStatin
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 10-12 )