Application and prospect of genetic testing technology in the selection of personnel working in extreme environments
WANG Heran
QUAN Jing
WU Yuanliang
WANG Heng
WANG Yue
Abstract：Genetic testing holds specific technical advantages in disease screening and health assessment,it has been increasingly applied in clinical medicine,particularly in precision health management.Extreme environments involve various complex and unique stress factors,including aerospace,polar area,deep sea and so on.These factors can induce and activate specific genes to undergo regulatory expression changes.Through genetic testing,mutations,susceptible gene types and functional loci can be identified,enabling analysis of individual and population adaptation mechanisms at the molecular functional level.However,due to constraints such as medical ethics,testing technology,and standards,genetic testing has not yet been officially applied in the selection of personnel working in extreme environments and related occupations.This article elaborates on the current advancements in genetic testing technologies,reviews recent discoveries on gene expression characteristics induced by various environmental factors in extreme settings,and prospects the potential advantages,limitations and future applications of genetic testing in selecting personnel working in extreme environments.
Keywords：genetic testingextreme environmentselection process
Publication Date：2026-02-25
Online Publishing Date：2026-03-26(First online date of this platform, not the publication date of the document)
Pages：10( 95-104 )