Analysis of functional connectivity characteristics of electroencephalogram network in different tolerance groups before and after sleep deprivation
YANG Haoping
YE Jiayu
QIN Haibo
XU Peng
CAO Ziqing
ZHANG Yue
CHI Lizhong
JIANG Lin
WU Bin
Abstract：Objectives In this study,we examined the differences in EEG activity between tolerant and intolerant subjects during the resting state and Flanker task,and the effects of 24-hour sleep deprivation on cognitive control.Methods In this study,a total of 39 volunteers were recruited.Seven cases were excluded or dropped out,and 32 cases were included in the statistical analysis(16 in the tolerance group and 16 in the intolerance group).Electroencephalogram measurements were conducted in the resting state and under the Flanker task before and after 24-hour sleep deprivation,respectively.Results The intolerant group showed significant cognitive decline after sleep deprivation,whereas the tolerant group maintained stable cognitive performance after sleep deprivation.Brain network analysis showed that the intolerance group showed hyperconnectivity characteristics in high frequency bands(Beta and Gamma)at baseline,while these connectivity were significantly decreased after sleep deprivation,especially in Gamma band.The tolerant group showed enhanced connectivity in the Theta and Alpha bands under the task.By combining spatial pattern network(SPN)features,the classification performance of linear discriminant analysis(LDA)was significantly improved before and after SD,especially in the Flanker task inconsistency condition,which further verified the effectiveness of SPN features in distinguishing tolerant and non-tolerant populations.Conclusion this study reveals a new perspective on the effects of sleep deprivation on cognitive function,and provides a new basis for the identification of tolerant and non-tolerant populations after sleep deprivation.
Keywords：sleep deprivationbrain networkcognitive controlspatial pattern networklinear discriminant analysis
Publication Date：2025-12-25
Online Publishing Date：2026-01-15(First online date of this platform, not the publication date of the document)
Pages：8( 513-520 )