Effects of 45 d-6 ° Head-down Bed Rest on Human Cardiopulmonary Function and Protection of Rhodiolarosea
Abstract：Objective To determine the effects of 45 d-6°head-down bed rest (HDBR) on cardiorespiratory function and protection of Rhodiolarosea on them.Methods Sixteen healthy adult male volunteers participated in the experiment of 45 d-6°HDBR and were divided into two groups randomly.During 45 d-6°HDBR,treatment group (n =8) took Hongyi capsules,while control group (n =8) took placebo capsules every day.The tests of exercise cardiopulmonary function and ECG was conducted before,during and after HDBR.Results Compared with pre-HDBR,1) 45th day during-6°HDBR the maximal oxygen consumption of control group significantly decreased (-18.26％;P ＜0.01) after 45 d HDBR,while there was no significant difference in that of treatment group (-10.04％;P ＞ 0.05);2) the maximal oxygen consumption per kilogram of control group significantly reduced on 30th or 45th day during and 10th day after HDBR (P ＜ 0.01),but that of treatment group less decreased and did not have statistical difference at these different time points (P ＞ 0.05);3) the maximal heart rate of control group and treatment group showed no significant change during HDBR,whereas that of control group (P ＜ 0.05) but not treatment group (P ＞ 0.05) significantly decreased on l0th day after HDBR.Conclusion 45 d-6° HDBR results in significant decreased in cardiorespiratory function and the traditional Chinese medicine,Hongyi capsules,can effectively prevent the simulated weightlessness-reduced human cardiorespiratory function.
Keywords：HDBRHongyi capsulesmaximal oxygen consumptionmaximal oxygen consumption per kilogrammaximal heart rate
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)