Fitting APD Restitution with Artificial Neural Network
HAN Xiao-dong
FANG Zu-xiang
YANG Cui-wei
WU Xiao-mei
Abstract：Objective To study the complex restitution relation between the present action potential duration (APD) and its previous diastole interval (DI) and APD. Method The Luo-Rudy model was paced with different protocols to draw the coordinate curves between the present APD and its first previous DI. These curves were fit with the artificial neural network (ANN). Result Different pacing protocols caused different coordinate curves, and there was no one-to-one relation between pre-sent APD and its first previous DI. ANN fits these curves satisfactorily. Conclusion There is a complex relation between the present APD and the APDs and Dis of the first three previous beats. This relation can be modeled accurately with ANN.
Keywords：ventricular fibrillationLuo-Rudy modelaction potential duration restitutionartificial neural network
Publication Date：2006-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 319-323 )