Effects of Tail Suspension on Electrophysiological Characteristics of Muscle Spindles in Isolated Rat Soleus Muscle
Abstract：Objective To study changes in electrophysiological characteristics of muscle spindles induced by simulated weightlessness in isolated rats soleus. Method Weightlessness was simulated by tail-suspension in female rats. Using electro-physiological technique,the spontaneous discharge of muscle spindle and its response to ramp-and-hold stretch were observed in isolated soleus of 7 d,14 d tail-suspended and control rats. Result Soleus muscle spindles of rat manifest a sharp decrease in spontaneous discharge frequency and the response to ramp-and-hold stretch after 7 d tail-suspension. More significant changes were observed in rats after 14 d tail-suspension. Conclusion Simulated weightlessness could induce time-related changes in electrophysiological characteristics of soleus muscle spindles in rat.
Keywords：weightlessness simulationtail suspensionsoleusmuscle spindleselectrophysiology
Publication Date：2004-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1-6 )