An Improved Portable Fiber Optic Sensor for Continuous Clinical Monitoring of Entero-gastric Reflux
Abstract：Objective To develop a method for on-line continuous monitoring of entero-gastric reflux in clinical diagnosis. Method Development of a fiber optic sensor for clinical monitoring of entero-gastric reflux based on characteristic absorption of bilirubin at analytical wavelength was reported in detail. The whole measuring system was composed of two LEDs as light sources, a bifurcated optic bundle and a detection circuit. Result A wonderful dynamic response with a linear range of up to 10 mg/dl was achieved. The pH effect on sample analysis was investigated and the in-vitro test demonstrated that the sensor worked preferably in acid environment. In vitro analyses of bile sample were carried out using the sensor. Conclusion The sensor shows good accuracy and sensitivity. With further development, the sensor can be made easily transportable, compact and inexpensive for biomedical analysis.
Keywords：fiber optical sensorsentero-gastric refluxbilirubinbile
Publication Date：2003-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 317-321 )