Effects of Simulated Weightlessness on T Cell Subpopulations and Activity of IL-2 and IL-6 in Mice
Abstract：Objective To observe the effects of simulated weightlessness on the immunogenic activities in mice. Method T cell subpopulations and the activity of IL-2 and IL-6 were observed in mice after exposure to head-down(-30°) tail suspension for 3 d and 7 d. Result The activity of IL-2 and IL-6 in mice showed no change after simulated weightlessess for 3 d compared with the control group.But after simulated weightlessness for 7 d,CD+3 and CD+4 were markedly reduced (both P<0.01) and CD+8 and CD+4/CD+8 also tended to decrease;the activity of IL-2 was significantly decreased,while the activity of IL-6 tended to increase. Conclusion Simulated weightlessness for 7 d had significant effcets on T cell subpopulations and the activity of certain cytokines in mice.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 60-62 )