The Role of Trauma and Hereditary Factors in Pulmonary Thromboembolism Secondary to Lower Extremity Deep Venous Thrombosis and Sudden Death:A Literature Review
CHI Yuxin
GAO Yuxiang
SHEN Zihan
SUN Yuqing
LIU Yujie
YANG Weihong
Abstract：Pulmonary thromboembolism(PTE)is one of the common causes of sudden unexpected death,with a high morbidity and mortality rate,seriously threatening patients' lives and health seriously.Trauma and genetic factors can lead to lower limb deep vein thrombosis(LDVT)secondary to PTE,and the mechanism of its occurrence has been a hot topic of research at home and abroad.In this article,we summarize trauma and genetic variation leading to LDVT secondary to PTE and sudden unexpected death by focusing on vascular endothelial damage,venous stasis and hypercoagulable state of the blood,so as to provide references for clinical prevention,treatment and forensic identification.
Keywords：pulmonary thromboembolismsingle nucleotide polymorphismsudden unexpected deathtraumalower limb deep vein thrombosis
Publication Date：2026-08-28
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 3070-3072,后插1 )