Effect of Multi-point Nerve Block Combined with Patient Controlled Intravenous Analgesia After Radical Surgery for Female Breast Cancer
YANG Weihua
ZHOU Jie
Abstract：Objective To observe the analgesic effects of multi-point nerve block combined with patient controlled intravenous analgesia(PCIA)after radical surgery for breast cancer in women.Methods A total of 60 patients who underwent radical surgery for breast cancer in Puyang People's Hospital from January 2020 to May 2024 were selected and divided into a combined group(multi-point nerve block combined with postoperative PCIA)and a PCIA group(postoperative PCIA)using a computer-generated random number table,with 30 cases in each group.The pain scores at 2,8,12,24,and 48 hours postoperatively,the first PCIA compression time,sufentanil dosage,PCIA compression frequency,analgesic satisfaction,and analgesic adverse reactions were compared between the two groups.Results There were no breakthrough pain or patients requiring rescue analgesia in both groups.Repeated measures analysis of variance showed that there was an interaction between the groups in terms of visual analogue scale(VAS)scores over time(P＜0.05).The VAS scores at 2,8,12,and 24 hours postoperatively in the combined group were lower than those in the PCIA group(P＜0.05).There was no significant difference in VAS scores at 48 hours postoperatively between the two groups(P＞0.05).Compared with 2 h after surgery,VAS scores at 8 h,12 h and 24 h were increased in both groups(P＜0.05),VAS scores at 48 h after surgery in the combined group was increased(P＜0.05),and VAS scores at 48 h after surgery in the PCIA group were decreased(P＜0.05).Compared with 8 h after surgery,VAS scores at 12 h were increased in both groups(P＜0.05),and VAS score at 48 h after surgery in the PCIA group was decreased(P＜0.05).Compared with 12 h after surgery,VAS scores at 24 h and 48 h were decreased in both groups(P＜0.05).Compared with 24 h after surgery,VAS scores at 48 h were decreased in both groups(P＜0.05).The first PCIA compression time in the combined group was longer than that in the PCIA group(P＜0.05),and the sufentanil dosage and PCIA compression frequency were lower than those in the PCIA group(P＜0.05).The analgesic satisfaction in the combined group was higher than that in the PCIA group(P＜0.05).There were no significant differences in the incidence of headache,nausea and vomiting,hallucinations,rash,and respiratory depression and the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Multi-point nerve block combined with PCIA can alleviate postoperative pain in women undergoing radical breast cancer surgery,reduce the dosage of PCIA,improve analgesic satisfaction,and does not significantly increase adverse reactions.
Keywords：breast cancer radical surgerynerve blockpatient controlled intravenous analgesiaanalgesic effect
Publication Date：2026-08-28
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：5( 2957-2961 )