Effect of Flexible Ureteroscopic Holmium Laser Lithotripsy Assisted by 3D Printing Technology on Calyceal Diverticulum Calculi
SONG Weihang
ZHANG Chunfeng
LIU Pei
LI Zeyu
HAN Guangye
Abstract：Objective To investigate the effect of 3 D printing technology assisted flexible ureteroscopic holmium laser lithotripsy(FURL)in the treatment of calyceal diverticular calculi and its influence on surgical trauma index and renal function.Methods A total of 124 calyceal diverticulum calculi patients in the First Affiliated Hospital of Henan Medical University from May 2022 to August 2024 were selected and randomly divided into the 3D group and control group,with 62 cases in each group.The control group was treated with FURL,and the 3D group was treated with 3D printing technology to assist FURL.The stone clearance rate,operation and postoperative recovery were compared between the two groups,as well as the trauma indexes[norepinephrine(NE),cortisol(Cor),adrenocorticotropic hormone(ACTH),C-reactive protein(CRP)]and renal function indexes[blood urea nitrogen(BUN),serum creatinine(Scr),cystatin C(Cys-C),neutrophil gelatinase-associated lipocalin(NGAL)]before operation,1 day after operation and 3 days after operation.The incidence of postoperative complications during hospitalization was recorded,and the stone recurrence rate was counted after 1 year of follow-up.Results The stone clearance rate of 2-3 days after operation in the 3D group was 91.94％,which was higher than that in the control group(77.42％)(P＜0.05).The intraoperative blood loss of the 3D group was(25.27±5.13)mL,which was lower than that of the control group(38.19±6.44)mL.The operation time,postoperative ambulation time and hospitalization time were(44.81±7.26)min,(7.26±1.69)h and(3.48±0.80)d,respectively,which were less than those of the control group(57.43±10.02)min,(10.84±1.95)hand(4.27±0.92)d(P＜0.05).The levels of serum NE,Cor,ACTH,CRP,BUN,Scr,Cys-C and NGAL in the 3D group were lower than those in the control group before operation,1 d and 3 d after operation(P＜0.05).The incidence of postoperative complications during hospitalization and the recurrence rate of calculi within 1 year after operation in the 3D group were 3.23％and 3.33％,respectively,which were lower than 16.13％and 16.95％in the control group(P＜0.05).Conclusion 3 D printing technology assisted FURL in the treatment of caliceal diverticular calculi can improve the effect of stone removal,reduce the risk of postoperative recurrence,reduce surgical trauma and renal injury,reduce the incidence of complications,and facilitate early postoperative rehabilitation.
Keywords：caliceal diverticula calculi3D printing technologyflexible ureteroscopic holmium laser lithotripsycomplicationsrecurrence
Publication Date：2026-07-28
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：6( 2557-2562 )