Diagnostic Value of Echocardiography Combined with Brain Natriuretic Peptide,Creatine Kinase Isoenzyme-MB and Myoglobin in Acute Myocardial Infarction

ZU Hongli; WAN Qing; WANG Zheng

doi:10.3969/j.issn.1004-437X.2026.09.015

Abstract：Objective To explore and analyze the diagnostic value of echocardiography combined with brain natriuretic peptide(BNP),creatine kinase isoenzyme-MB(CK-MB)and myoglobin(Myo)in acute myocardial infarction.Methods A total of 98 patients with acute myocardial infarction admitted to Henan Hospital of Traditional Chinese Medicine from November 2021 to October 2023 were included as the observation group.In addition,80 healthy individuals who underwent outpatient physical examinations in Henan Hospital of Traditional Chinese Medicine were selected as the control group.All study subjects underwent echocardiography,CK-MB,Myo,BNP detection,and CK-MB,Myo,BNP levels,changes in cardiac function indicators,and combined diagnostic efficacy were compared between the two groups.Results The serological test results were showed that the observation group levels of CK-MB,Myo and BNP were both higher than those of the control group,with significant differences(P＜0.05).The results of functional testing indicators related to echocardiography were showed that compared with the control group,the observation group had higher levels of left ventricular end-diastolic diameter(LVEDD)and left ventricular end systolic diameter(LVESD),but left ventricular ejection fraction(LVEF)decreased(P＜0.05).According to receiver operating characteristic(ROC)curve analysis,four joint tests(the sensitivity of echocardiography,BNP,CK-MB,and Myo was 95.90％,the area under the curve(AUC)value was 0.984,which was higher than the sensitivity and AUC value of the four individual tests(P＜0.05).Conclusion After testing,BNP,CK-MB and Myo are abnormally highly expressed in the diagnosis of acute myocardial infarction.Combined detection with echocardiography can improve diagnostic efficiency and has important clinical significance.