Application of Flexile Bronchoscope in Diagnosis and Treatment of Children with Wheezing Diseases
LI Zeng
HUANG Shixia
Abstract：Objective To analyze the effect of flexile bronchoscope in the diagnosis and treatment of children with wheezing diseases.Methods From March 2022 to March 2024,a total of 118 children with wheezing diseases were selected for flexile bronchoscopy and treatment in the Department of Pediatrics of the First Hospital of Sanming Affiliated to Fujian Medical University.The etiology,age distribution of wheezing,etiology,and changes of their conditions before and after treatment with flexile bronchoscopy were analyzed.Results Among the 118 children,there were 28 cases of atelectasis,38 cases of endobronchial inflammation,20 cases of plastic bronchitis,19 cases of tracheomalacia and bronchial foreign bodies,8 cases of tracheomalacia,2 cases of bronchiectasis,2 cases of tracheal stenosis,1 case of base cyst of the tongue.For 1-3 years old children,apart from infectious factors,airway malformation could not be ignored as the cause of wheezing,and the incidence was higher than that of preschool and school-age children(P＜0.05).There was no significant difference in pathogen positive between alveolar lavage fluid culture and sputum culture(P＞0.05).Compared with the traditional detection of pathogen serum antibody,real-time fluorescent quantitative PCR in alveolar lavage fluid had a higher positive rate,better sensitivity and specificity(P＜0.05).The clinical symptoms,infection indicators and imaging changes before and after tracheoscopy were improved,and the curative effect was significant(P＜0.05).Conclusion Flexile bronchoscope can observe airway lesions clearly and intuitively,and can detect pathogen specificity and sensitivity by real-time fluorescent quantitative PCR with alveolar lavage fluid.It can remove airway secretions and foreign bodies in time,and improve wheezing symptoms rapidly.Therefore,flexile bronchoscope plays an indispensable role in the diagnosis and treatment of children with wheezing diseases.
Keywords：flexible bronchoscopewheezingalveolar lavage fluidairway malformation
Publication Date：2026-04-28
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 1367-1370 )