Diagnostic Value of Electrocardiographic Plane QRS-T Angle Combined with Serum sST2 and NT-proBNP in Myocardial Ischemia of Coronary Heart Disease
GUO Xiaoliang
SHEN Hang
Abstract：Objective To explore the diagnostic value of electrocardiographic plane QRS-T angle combined with serum soluble growth stimulation expressed gene 2 protein(sST2)and N-terminal pro-brain natriuretic peptide(NT-proBNP)in myocardial ischemia of coronary heart disease(CHD).Methods A total of 125 CHD patients admitted to the Fifth Affiliated Hospital of Zhengzhou University from June 2023 to June 2025 were selected.According to the results of myocardial ischemia examined by coronary angiography,they were divided into the ischemic group(92 cases)and the non-ischemic group(33 cases).All patients underwent dynamic electrocardiogram examination,sST2 detection and NT-proBNP detection.The general data,electrocardiographic plane QRS-T angle,serum sST2 and NT-proBNP levels were compared between the two groups.Receiver operating characteristic(ROC)curve was used to analyze the diagnostic values of electrocardiographic plane QRS-T angle,sST2,NT-proBNP alone and their combination in myocardial ischemia of CHD.Results There were no significant differences in general data such as gender,age and underlying diseases between the two groups(P＞0.05).The average electrocardiographic plane QRS-T angle in the ischemic group was larger than that in the non-ischemic group,and the serum sST2 and NT-proBNP levels in the ischemic group were also higher than those in the non-ischemic group(P＜0.05).ROC curve analysis showed that the area under the curve of electrocardiographic plane QRS-T angle for diagnosis was 0.841(95％CI:0.765-0.900),the area under the curve of sST2 was 0.880(95％CI:0.810-0.931),the area under the curve of NT-proBNP was 0.846(95％CI:0.770-0.904),and the area under the curve of the combined detection of the three indicators was 0.964(95％CI:0.915-0.989).Conclusion The electrocardiographic plane QRS-T angle and serum sST2 and NT-proBNP levels are increased in CHD patients with myocardial ischemia.The combined detection of the three indicators has high diagnostic value for myocardial ischemia.
Keywords：coronary heart diseasemyocardial ischemiaelectrocardiographic plane QRS-T anglesoluble growth stimulation expressed gene 2 proteinN-terminal pro-brain natriuretic peptide
Publication Date：2026-03-28
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 1012-1015 )