Comparison of the Effects of Two Different Perfusion Schemes in Endoscopic Submucosal Dissection for Patients with Colorectal Polyps
ZHAO Bin
LUO Hongwei
CHENG Lina
Abstract：Objective To explore the effects of two different perfusion schemes(carbon dioxide perfusion and air perfusion)in endoscopic submucosal dissection for patients with colorectal polyps.Methods A retrospective analysis was conducted on 98 patients with colorectal polyps diagnosed and treated with endoscopic submucosal dissection at Zhengzhou TCM Hospital in Henan Province from August 2019 to April 2023.Among them,49 patients who underwent carbon dioxide perfusion were included in the carbon dioxide group,and 49 patients who underwent air perfusion were included in the air group.The hemodynamics(mean arterial pressure,heart rate)at different time points,clinical indicators(operation time,anesthetic awakening time,complete resection rate),postoperative pain[assessed by numerical rating scale(NRS)at 6,12,and 24 hours after surgery],gastrointestinal recovery[assessed by gastrointestinal symptom rating scale(GSRS)at 1,3,and 7 days after surgery]were evaluated and compared between the two groups.Postoperative complications and recurrence were also analyzed.Results There were no statistically significant differences in mean arterial pressure and heart rate in time point,between-group,and interaction comparisons(P＞0.05).There were no statistically significant differences in clinical indicators between the two groups(P＞0.05).The NRS scores and GSRS scores of the carbon dioxide group were lower than those of the air group at various time points(P＜0.05).There were no statistically significant differences in the incidence of complications and recurrence rates between the two groups(P＞0.05).Conclusion Patients with colorectal polyps treated with endoscopic submucosal dissection can achieve stable hemodynamics and ideal surgical results with different perfusion schemes during surgery.However,carbon dioxide perfusion helps to reduce postoperative pain and is more conducive to postoperative gastrointestinal function recovery.
Keywords：colorectal polypsendoscopic submucosal dissectioncarbon dioxide perfusionair perfusiongastrointestinal functionpain
Publication Date：2026-03-13
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 829-832 )