Clinical Effect of Subacromial Injection of Platelet Rich Plasma Combined with Sodium Hyaluronate to Repair Rotator Cuff Injury

XU Changbo; HU Mingxin; XING Linqing

doi:10.3969/j.issn.1004-437X.2025.08.010

Abstract：Objective To investigate the clinical efficacy of platelet rich plasma(PRP)combined with sodium hyaluronate in repair of rotator cuff injury.Methods Sixty patients diagnosed with rotator cuff injury in the Department of Orthopedics of Zhengzhou People's Hospital from May 2020 to May 2021 were selected and divided into PRP group(30 cases)and control group(30 cases)according to random number table method.The PRP group received subacromial injection of 5 mL PRP combined with 2.5 mL sodium hyaluronate,and the control group received 2.5 mL sodium hyaluronate injection and 5 mL of normal saline.The same brand of PRP production equipment was used in both groups,and the same postoperative rehabilitation program was used to record the visual analogue scale(VAS),Constant-Murley score(CMS)of the European shoulder association,American shoulder and elbow surgeons(ASES)score before treatment and one month after treatment.Results There was no significant difference in general data between the two groups(P＞0.05).One patient in the PRP group was lost to follow-up due to refusal to come to the hospital for reexamination.There was no significant difference in VAS score,CMS score and ASES score between the two groups before treatment(P＞0.05).The VAS score decreased,CMS score increased,and ASES score increased in the PRP group 1 month after treatment compared to before treatment(P＜0.05).The VAS score decreased,CMS score increased,and ASES score increased in the control group one month after treatment compared to before treatment(P＞0.05).Conclusion PRP combined with sodium hyaluronate has an effective effect on the repair of rotator cuff injury.It can relieve the pain,improve the function of patients and promote the repair of rotator cuff.The operation is simple and convenient.