Effect of Botulinum Toxin Injection Combined with Body-Weight Supported Treadmill Training on Lower Limb Motor Function,Balance Ability and Gait in Children with Spastic Cerebral Palsy
JIN Panfeng
XIONG Huachun
WANG Yiwen
TANG Guohao
MENG Wenbin
ZHAO Huiling
FENG Huanhuan
Abstract：Objective To investigate the effect of botulinum toxin injection combined with body-weight supported treadmill training(BWSTT)on lower limb motor function,balance ability and gait in children with spastic cerebral palsy(SCP).Methods A total of 70 children with SCP admitted to the Third Affiliated Hospital of Zhengzhou University from May 2022 to February 2024 were randomly divided into two groups with 35 patients each.The control group was treated with BWSTT,and the observation group was treated with botulinum toxin injection on this basis.The scores of Fugl-Meyer assessment-lower extremity(FMA-LE),Berg balance scale(BBS)and gait(step length,step speed and step width)were compared between the two groups before and after treatment.Results After treatment,the FMA-LE scores were increased in the two groups,and the FMA-LE score in the observation group was higher(P＜0.05).After treatment,the BBS scores were increased in the two groups,and the BBS score in the observation group was higher(P＜0.05).After treatment,the levels of step length and speed increased,while the level of step width decreased in the two groups,and the levels of step length and speed were higher,while the level of step width was lower in the observation group(P＜0.05).Conclusion Botulinum toxin injection combined with BWSTT can effectively improve the lower limb motor function,balance ability,and gait in children with SCP,and this treatment has a great clinical application prospect.
Keywords：spastic cerebral palsybody-weight supported treadmill trainingbotulinum toxinlower limb motor functionbalance abilitygait
Publication Date：2025-03-28
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 983-986 )