Clinical Effect of Intracavitary Radiofrequency Ablation Combined with Foam Sclerosing Agent Injection in the Treatment of Varicose Veins of Lower Extremities
ZHANG Wei
Abstract：Objective To compare the clinical effects of intracavitary rad iofrequency ablation(RFA)combined with injection of foam sclerosing agent with spot stripping in the treatment of vriose veins of lower extremity(VVLE).Methods A total of 101 patients with VVLE in the Puyang People's Hospital from March 2021 to July 2023 were retrospectively analyzed.According to the different treatment methods,they were divided into the combined group(RFA combined with foam sclerosing agent injection,50 cases)and the spot stripping group(spot stripping,51 cases).The curative effect,inflammatory indexes[interleukin-6(IL-6),interleukin-17(IL-17),tumor necrosis factor-α(TNF-α)],hemorheology indexes[blood viscosity,fibrinogen,low shear whole blood viscosity]and Aberdeen varicose vein questionnaire(AVVQ)score were evaluated before and 3 months after operation.Results There was no statistical significant difference in the total effective rate between the two treatment groups(P＞0.05).At 3 months after operation,the levels of IL-6,IL-17 and TNF-α in the two groups were lower than those before operation,and those in the combined group were lower than the point stripping group(P＜0.05).At 3 months after operation,the levels of blood viscosity,fibrinogen and low-cut whole blood viscosity in the two groups decreased,and those in the combined group were lower than the point stripping group(P＜0.05).Compared to before treatment,the AVVQ scores of the two groups decreased,and the combined group was lower than the spot stripping group(P＜0.05).Conclusion The efficacy of spot stripping is equivalent to that of RFA combined with foam sclerosing agent injection in the treatment of VVLE,but RFA combined with foam sclerosing agent injection is more effective in improving hemorheological indicators and inflammatory indicators,helping to improve the quality of life of patients.
Keywords：vriose veins of lower extremityintracavitary radiofrequency ablationfoam sclerosing injectionspot strippingsecurity
Publication Date：2025-02-28
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 661-664 )