Comparison of Clinical Effects on Pneumatic Mediastinoscopy and Thoracoscopic Combined with Laparoscopic Surgery in the Treatment of Early Esophageal Cancer
LU Wanli
WANG Jungang
HAO Mengfu
Abstract：Objective To analyze the clinical application of pneumatic mediastinoscopy and thoracoscopic combined with laparoscopic surgery in the treatment of early esophageal cancer.Methods A total of 86 patients with early esophageal cancer who underwent surgical treatment in Nanyang Central Hospital from June 2019 to January 2022 were selected for the study.According to the surgical method,they were divided into control group(receiving thoracoscopy combined with laparoscopic esophageal cancer resection,42 cases)and observation group(receiving inflatable mediastinoscopy combined with laparoscopic esophageal cancer resection,44 cases).The operation related indexes,pulmonary function indexes[forced vital capacity percentage of predicted value(FVC％),maximum voluntary ventilation percentage of predicted value(MVV％),maximum expiratory volume percentage of predicted value(FEV％)],inflammatory indexes[interleukin-6(IL-6),interleukin-8(IL-8),interleukin-10(IL-10)],incidence of complications and recurrence rate were compared between the two groups.Results Compared with the control group,the observation group had less intraoperative blood loss,less drainage volume at 1 day after operation,shorter chest tube removal time,and shorter postoperative hospital stay(P＜0.05).After surgical treatment,the levels of FVC％,MVV％,FEV％,IL-6,IL-8 and IL-10 in the two groups showed a decreasing trend,and compared with the control group,the levels of FVC％,MVV％and FEV％in the observation group were higher,and the levels of IL-6,IL-8 and IL-10 were lower(P＜0.05).There was no difference in the incidence of postoperative complications and 1-year recurrence rate between the two groups(P＞0.05).Conclusion Pneumatic mediastinoscopy combined with laparoscopic esophageal cancer resection can reduce surgical trauma,improve surgical indicators,reduce damage to lung function,and reduce the level of inflammatory factors,which is worthy of clinical promotion.
Keywords：early esophageal cancerpneumatic mediastinoscopy:thoracoscopiclaparoscopy
Publication Date：2025-02-14
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 460-463 )