Effect of Combined Anti-osteoporotic Treatment of PFNA and Inter Tan Internal Fixation in Patients with Osteoporotic Intertrochanteric Femur Fracture
LI Yuhua
MA Zikun
FENG Zipan
ZHAI Gongwei
FAN Zhiyuan
Abstract：Objective To observe the effect of proximal femoral anti-rotational intramedullary nailing(PFNA)and Inter Tan internal fixation combined with anti-osteoporotic treatment on hip function and postoperative bone healing indexes in patients with osteoporotic intertrochanteric femoral fractures.Methods Sixty patients with osteoporotic intertrochanteric femur fractures who attended People's Hospital of Zhengzhou from January 2020 to April 2023 were divided into two groups by randomization method,the PFNA group received PFNA internal fixation combined with anti-osteoporosis treatment,and the Inter Tan group received Inter Tan internal fixation combined with anti-osteoporosis treatment.The clinical outcomes of the two groups were compared.Results Weight-bearing activity time[(60.88±8.41)weeks],early time to walk on the ground[(5.94±1.07)d]in Inter Tan group were shorter than those in the PFNA group,incision length[(8.61±0.87)cm]was smaller than in the PFNA group,the number of intraoperative fluoroscopies[(4.95±0.94)times],intraoperative bleeding[(204.15±26.22)mL]in Inter Tan group were more than those in the PFNA group,the number of hemoglobin(Hb)[(18.56±4.74)g•L-1]and hematocrit(Hct)decreased value[(4.16±0.59)％]were higher than those of PFNA group,and the operation time[(123.26±23.36)min]was longer than that of PFNA group,and the difference was statistically significant(P＜0.05).Harris score and alkaline phosphatase(BALP),total type Ⅰ collagen amino-terminal extended peptide(tP ⅠNP),osteocalcin(OC)were higher than preoperative at 24 weeks after surgery in both groups,and visual analog scale(VAS)score and type Ⅰ collagen carboxy-terminal peptide β-special sequence(β-CTX)were lower than preoperative,and the difference was statistically significant(P＜0.05).Harris score of Inter Tan group was higher than that of PFNA group,and VAS score of Inter Tan group was lower than that of PFNA group 24 weeks postoperative,and the difference was statistically significant(P＜0.05).The anatomical repositioning excellence rate of Inter Tan group was higher than that of PFNA group,and the internal fixation loosening rate was not statistically significant when compared with that of PFNA group(P＞0.05).Conclusion Compared with Inter Tan internal fixation and PFNA internal fixation combined with anti-osteoporosis in the treatment of intertrochanteric fracture with osteoporosis,Inter Tan internal fixation has a small incision,good postoperative recovery of hip function,and a high rate of excellent postoperative anatomical restoration,but has a long operative time,and the number of intraoperative fluoroscopies is relatively high.
Keywords：osteoporosisintertrochanteric fracture of the femuranti-rotational intramedullary nailing of the proximal femurInter Tan internal fixation
Publication Date：2025-02-14
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：5( 444-448 )