Clinical Efficacy of Micro Skin Grafting and Stamp Skin Grafting in the Treatment of Large Area Burns

HE Yongqiang; ZHANG Yan

doi:10.3969/j.issn.1004-437X.2025.03.011

Abstract：Objective To explore the curative effect of micro skin grafting and stamp skin grafting in the treatment of large area burn and its influence on the survival rate of skin grafting and wound healing.Methods A total of 83 cases of patients with large area burn treated in Henan Electric Power Hospital from January 2022 to December 2023 were selected as the research object,and they were divided into stamp group(44 cases)and microparticle group(39 cases)according to different surgical methods.The former underwent stamp skin grafting technology,and the latter underwent microparticle skin grafting.The operation indexes and survival rate of skin graft were compared between the two groups,as well as oxidative stress[malondialdehyde(MDA),interleukin-1β(IL-1β),super oxide dismutase(SOD)],quality of life and complications before and after operation.Results Compared with the microparticle group,the stamp group had less treatment cost,shorter wound healing time,hospital stay and operation time(P＜0.05).One week after operation,the survival rate of skin grafting in the two groups(97.73％vs 82.05％)was significantly different(P＜0.05).One week after operation,compared with the microparticle group,the levels of serum MDA,IL-1 β and SOD in the stamp group were lower(P＜0.05).Two weeks after operation,the quality of life in the stamp group was better than that in the microparticle group(P＜0.05).There was no significant difference in the incidence of complications between the two groups(2.27％vs 7.69％)(P＞0.05).Conclusion Stamp skin grafting technique can improve the survival rate of skin grafting,shorten the wound healing time,reduce the body's oxidative stress reaction and has good safety in patients with large area burn.