Related Factors and Preventive Measures of Severe Cases in Children with Hand Foot Mouth Disease Infected with EV-A71
SHAO Qingqing
ZHANG Xin
ZHANG Lin
Abstract：Objective To explore the related factors and preventive measures of severe hand,foot and mouth disease in children infected with enterovirus A71(EV-A71).Methods The medical records of 116 children with hand,foot and mouth disease infected with EV-A71 in Zhengzhou People's Hospital from October 2020 to February 2022 were retrospectively analyzed.According to the severity of the disease,they were divided into mild disease group(86 cases)and severe disease group(30 cases).The basic clinical data of all subjects were collected and sorted out.The risk factors of severe disease in children with hand,foot and mouth disease infected with EV-A71 were analyzed by logistic regression.Results In the severe group,the proportion of residents living at the junction of urban and rural areas,the time from onset to diagnosis＞3 days,the highest temperature of fever≥39 ℃,and the proportion of guardians with junior middle school education level or below were higher than those in the mild group(P＜0.05).The results of logistic multiple regression analysis showed that the risk factors for severe cases of children with hand,foot and mouth disease caused by EV-A71 infection were the urban-rural junction,the time from onset to diagnosis＞3 days,the maximum temperature of fever≥39 ℃,and the educational level of guardians at or below junior high school(P＜0.05).Conclusion The place of residence of critically ill children is mainly at the junction of urban and rural areas.The diagnosis within 3 days of onset is the key period to prevent the progress of the disease.The maximum temperature of fever≥39 ℃ is one of the early identification indicators of severe cases.The education level of guardians at or below junior high school is not conducive to the prevention and control of the disease.It is an effective measure to reduce the occurrence of severe cases to actively carry out health education and publicity activities for key areas in the urban-rural fringe of residence and key groups with low educational level of guardians,and to practice the treatment scheme of early detection,early diagnosis and early treatment.
Keywords：hand foot mouth diseaseenterovirus A71severerisk factorpreventive measure
Publication Date：2025-01-29
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 260-263 )