Analysis of High-Risk Factors and Corresponding Prevention Strategies for Pulmonary Infection in Critically Ill Patients with Heart Failure

WANG Shu; NIE Ming; LIU Jianmin

doi:10.3969/j.issn.1004-437X.2025.01.017

Abstract：Objective To explore the high-risk factors and corresponding prevention strategies for pulmonary infection(PI)in critically ill patients with heart failure(HF).Methods The clinical data of 188 critically ill patients with critical HF treated at Anyang People's Hospital from January 2021 to May 2023 were retrospectively analyzed.The selected patients were divided into the infected group(76 cases)and the uninfected group(112 cases)according to whether they had PI.The clinical data of the two groups were compared,and the risk factors of PI in critically ill patients with critical HF were analyzed by multivariate logistic regression analysis.Results The proportion of patients with aged ≥60 years,smoking,having a history of hypertension,chronic obstructive pulmonary disease(COPD),diabetes,antibiotic or hormone abuse,left ventricular ejection fraction(LVEF)＜35％,and LVEF 35％-54％in the infected group were higher than the uninfected group,the time of hospital stay was longer than that of the uninfected group,the level of serum C-reactive protein(CRP)was higher than that of the uninfected group(P＜0.05).Multivariate logistic regression analysis showed that the independent risk factors for PI in critical HF patients included age ≥60 years,smoking,history of COPD,history of diabetes,abuse of antibiotics or hormones,LVEF＜35％,and long time of hospital stay(OR=2.221,6.456,2.479,1.929,1.931,2.479,2.408,P＜0.05).Conclusion The independent risk factors for PI in critical HF patients included age ≥60 years,smoking,history of COPD,history of diabetes,abuse of antibiotics or hormones,LVEF＜35％,and long time of hospital stay.