Analysis of Urinary Calculi Component Characteristics in Henan Province
YAO Xiaoyan
XU Qiaoqiao
QIN Jielin
LI Xianghui
LIU Chuang
Abstract：Objective To summarize and analyze the characteristics of urolithiasis components in Henan,and to provide evidence for the prevention of lithiasis in Henan.Methods The calculi composition data of 1 636 urinary calculi samples from different patients collected from the First Affiliated Hospital of Zhengzhou University from January 2017 to December 2023 were retrospectively analyzed,and their characteristics were described.Results A total of 1 636 patients were included in this study,the ratio of male to female was 2.28∶1,and the mean age was(45.5±14.1)years.Urinary calculi were mainly located in the upper urinary tract,among which kidney calculi were the most common,accounting for 67.5％of the total population.Urinary stones were the most common in young adults,accounting for 81.7％of the total population.The most common component of urinary calculi was calcium oxalate calculi,accounting for 81.0％of the total population.There was significant difference in classification and composition of stones between different genders(x2=45.476,P＜0.001).The proportion of calcium oxalate stones was higher in male patients(83.2％vs 76.0％,P=0.001),while the proportion of apatite carbonate,magnesium ammonium phosphate and calcium hydrogen phosphate stones was higher in female patients,and the differences were statistically significant(P＜0.05).The classification and composition of stones in different periods were significantly different(x2=57.542,P＜0.001).In recent 3 years,the proportion of magnesium ammonium phosphate stones and cystine stones increased significantly,while the proportion of calcium oxalate stones,apatite carbonate stones and calcium hydrogen phosphate stones decreased,with statistical significance(P＜0.05).The differences of calcium oxalate calculus,uric acid calculus and ammonium magnesium phosphate calculus in different parts were statistically significant(P＜0.05).Calcium oxalate stones were common in upper urinary tract stones,uric acid stones and magnesium ammonium phosphate stones were more common in bladder stones.The distribution of calcium oxalate stones,uric acid stones and calcium hydrogen phosphate stones in different age groups had statistical significance(P＜0.05).Calcium oxalate stones were more common in young adults,uric acid stones were more common in the elderly and children,and calcium hydrogen phosphate stones were more common in children.Conclusion The characteristics of urinary calculi components in Henan area are that gender,age,location of calculi and different periods of patients have an impact on urinary calculi components.This finding may help to improve the understanding of pathophysiology of urinary calculi components in Henan area and provide scientific basis for the prevention of calculi.
Keywords：stone compositionHenan Provinceretrospective analysis
Publication Date：2024-11-15
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：5( 3849-3853 )