Influencing Factors of MACE After PCI in Young Patients with Acute Coronary Syndrome and Its Relationship with Gensini Score
HAN Long
YE Zhishuai
LI Shouzhen
XU Tan
Abstract：Objective To analyze the influencing factors of major adverse cardiovascular events(MACE)in young patients with acute coronary syndrome(ACS)after percutaneous coronary intervention(PCI)and their relationship with Gensini score.Methods A total of 198 young patients with ACS admitted to Xinyang Central Hospital from June 2021 to June 2022 were selected as the study objects.All of them underwent PCI and were followed up for 1 year after surgery.Six cases were lost to follow up,and a total of 192 cases completed the follow-up,and MACE were recorded.According to whether MACE occurred,the patients were divided into MACE group(35 cases)and non-MACE group(157 cases).General data and Gensini scores of all subjects were collected and compared to analyze the influencing factors and the correlation between Gensini scores and disease outcomes.Results There were statistical differences in hypertension,stent diameter,number of implanted stents,cardiac troponin I(cTnI),obesity,creatine kinase isoenzyme MB(CK-MB),homocysteine(HCY)and Gensini scores in two group(P＜0.05).Multivariate analysis showed that the number of implanted stents＞1,cTnI ≥8.76 μg·L-1,CK-MB ≥25.93 U·L-1,HCY ≥12.55 μmol·L-1,and Gensini score ≥13.85 were the risk factors for MACE in young ACS patients after PCI,stent diameter ≥3.07 mm was a protective factor for MACE in young ACS patients after PCI(P＜0.05).The number of implanted stents,cTnI,CK-MB and Gensini scores were positively correlated with the disease outcome,while the stent diameter was negatively correlated with the disease outcome(P＜0.05).Conclusion The risk of MACE in young ACS patients after PCI is affected by multiple factors,and the number of implanted stents,stent diameter,cTnI,CK-MB,HCY and Gensini scores are directly correlated with disease outcome,which can provide guidance for clinical development of early prevention and treatment measures.
Keywords：acute coronary syndromecoronary interventionGensini scoredisease outcome
Publication Date：2024-10-31
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 3721-3724 )