Dynamic Blood Pressure Variability and Its Relationship with Cardiac Structure and Pumping Function in Elderly Patients with Essential Hypertension

ZHAI Xianghong

doi:10.3969/j.issn.1004-437X.2024.12.011

Abstract：Objective To explore the relationship with cardiac structure,pumping function and dynamic blood pressure variability in elderly patients with essential hypertension(EH).Methods A total of 126 elderly patients with EH who received treatment at Zhengzhou Traditional Chinese Medicine Hospital from January 2021 to December 2022 were selected as group A.Among them,79 patients with H-type hypertension(HT)were in the H-type HT group,47 patients with non-H-type HT were in the non-H-type HT group.A total of 130 non-HT elderly patients admitted during the same period were selected as group B.The dynamic blood pressure variability indicators,pumping function and cardiac structure between the group A and the group B,the dynamic blood pressure variability indicators,cardiac structure and pumping function between the H-type HT group and the non-H-type HT group were compared.The correlation between cardiac structure,pumping function,and dynamic blood pressure variability indicators in elderly patients with primary HT were analyzed by Spearman correlation analysis.Results The standard deviation of nighttime systolic blood pressure(N-SSD),24-hour systolic blood pressure(24 h SSD),and daytime systolic blood pressure(D-SSD)in the group A were all higher than those in the group B(P＜0.05).The stroke volume,cardiac output and interventricular septum thickness in the group A were higher than those in the group B,and the left ventricular ejection fraction(LVEF)and left ventricular posterior wall thickness in the group A were lower than those in the group B(P＜0.05).Compared with the non-H-type HT group,the 24 h SSD,N-SSD,D-SSD and stroke volume,cardiac output and interventricular septum thickness in the H-type HT group were higher;the LVEF and left ventricular posterior wall thickness in the H-type HT group were lower(P＜0.05).Stroke volume in elderly patients with EH was positively correlated with 24 h SSD,N-SSD,and D-SSD in elderly patients with EH(r=0.548,0.508,0.487),while cardiac output was positively correlated with 24 h SSD,N-SSD,and D-SSD(r=0.612,0.573,0.490).LVEF was negatively correlated with 24 h SSD,N-SSD,D-SSD(r=-0.603,-0.489,-0.543).The thickness of interventricular septum was positively correlated with 24 h SSD,N-SSD,D-SSD(r=0.576,0.645,0.476).The thickness of the left ventricular posterior wall was negatively correlated with 24 h SSD,N-SSD,and D-SSD(r=-0.524,-0.603,-0.498)(P＜0.05).Conclusion The ambulatory blood pressure variability,cardiac structure and blood pumping function of different types of elderly patients with EH were different.The 24 h SSD,N-SSD,D-SSD of patients were positively correlated with stroke volume,cardiac output,and interventricular septum thickness,and negatively correlated with LVEF and left ventricular posterior wall thickness.