Memory-Guided Saccades Study on Patients with Vascular Cognitive Impairment No Dementia
ZHANG Kai
LI Ping
Abstract：Objective To study the characteristics of memory-guided saccades(MGS)in patients with vascular cognitive impairment no dementia(VCIND)and to investigate the value of MGS in detecting cognitive function in the patients.Methods A total of 44 patients with VCIND from the Department of Neurology of Puyang People's Hospital from January 2022 to February 2023 were selected as the case group,while 80 healthy subjects were selected as the control group.The classical MGS was performed by videonystagmography,and the test results were compared.The observation indicators included MGS velocity,latency and accuracy of 10°,15° and 20°of left and right at 6 angles.Results There was no statistically difference in MGS velocity between the two groups(P＞0.05).The MGS latency in the case group was longer(P＜0.05 for all directions and angles except for the leftward 15° P=0.094),and the accuracy of MGS was decreased(P＜0.05 for all directions and angles except rightward 10° P=0.079).Conclusion MGS abnormalities in patients with VCIND,mainly manifested by prolonged latency and decreased accuracy.MGS provides objective electrophysiological indicators,and with certain auxiliary diagnostic value.
Keywords：vascular cognitive impairment no dementiamemory-guided saccadescognitivelatencyaccuracyvideonystag-mography
Publication Date：2023-12-31
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：5( 4491-4495 )