Predictive Value of FAR,eGFR,HbA1c,Cys-C for Contrast Associated Nephropathy After Percutaneous Coronary Intervention
YAO Wei
MA Guang
HE Zhaohui
Abstract：Objective To explore the predictive value of fibrinogen to albumin ratio(FAR),glomerular filtration rate(eGFR),glycosylated hemoglobin(HbA1c),cystatin C(Cys-C)on contrast associated nephropathy(CAN)after percutaneous coronary intervention(PCI).Methods A total of 86 patients with acute myocardial infarction who underwent PCI in the hospital from February 2020 to October 2022 were selected as the study subjects.They were divided into CAN group(25 cases)and non-CAN group(61 cases)based on whether postoperative CAN occurred.FAR,eGFR,HbA1c,Cys-C were compared.Using logistic regression models to establish a joint prediction model for FAR,eGFR,HbA1c,Cys-C.The receiver operating characteristic(ROC)model was used to analyze the area under the curve(AUC)value,sensitivity and specificity of FAR,eGFR,HbA1c,Cys-C and the combination of four factors in predicting contrast nephropathy after PCI.Results The FAR,HbA1c,Cys-C of the CAN group were higher than those of the non-CAN group,while eGFR was lower than that of the non-CAN group(P＜0.05).The ROC analysis showed that the AUC values of FAR,eGFR,HbA1c,Cys-C and the four combined predictors of contrast agent nephropathy after PCI were 0.617,0.766,0.744,0.669,0.929,respectively(P＜0.05).Conclusion FAR,eGFR,HbA1c and Cys-C are highly expressed in patients with CAN after PCI,and detecting their changes is of great significance in predicting the occurrence of postoperative contrast-enhanced nephropathy.
Keywords：contrast associated nephropathyratio of retinogen to albuminglomerular filtration rateglycosylated hemoglobincystatin Cpercutaneous coronary interventioncontrast nephropathy
Publication Date：2023-12-31
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 4481-4484 )