Analysis of 500 cases of diabetic nephropathy 1 year after discharge
Cai Jinpeng
Jiang Hongwei
Abstract：Objective To evaluate the risk factors of diabetic nephropathy (DN) and provide a theoretical basis for improving the prognosis and prognosis of DN by exploring the status and problems of DN patients after discharge.Methods The clinical data of 612 patients with DN who were admitted to the First Affiliated Hospital of Henan University of Science and Technology from January of 2014 to September of 2015 were followed up for one year, and 530 eligible patients were screened out.During a follow-up period of 1 year, a total of 30 cases were lost, and 500 cases were as statistically valid samples.The patients were divided into different groups according to the standard diet, blood glucose, blood pressure, blood lipid and regular medication situation within one year.The incidence of disease progression events (including DN from stage Ⅲ to stage Ⅳ, DN from stage Ⅳ to stage Ⅴ, SCr increased by one time, receiving dialysis treatment, death caused by DN and so on), urinary protein quantity in 24 hours, the expression levels of HCY, hs-CRP, CysC were compared.Results After 1 year of follow-up, the incidence of DN progression events was 10.8% (54 cases) in 500 patients, and the rate of DN progress events was 21.3% (34/160) in 160 patients with fasting blood glucose>7.0 mmol/L, hs-CRP (8.7±6.1) mg/L, HCY (9.6±2.7) μmol/L, CysC (3.1±1.4) mg/24 h, the levels of observed indicators were significantly higher than patients with the fasting blood glucose≤7.0 mmol/L.The incidence of DN progression events of those who did not follow a low protein diet, or have poor blood pressure control, or poor blood lipid regulation was higher than the average level(P<0.05).The expression of hs-CRP, HCY and CysC were significantly increased(P<0.05).Conclusion Patients with DN have irregular diet, poor compliance, blood pressure, blood glucose, blood lipid control and so on.Diet structure, rational use of drugs, blood glucose, blood pressure and blood lipid levels are the main risk factors for the development of DN.Lowering blood pressure and controlling blood sugar can slow down the development of DN.
Keywords：diabetic nephropathyblood glucosemedication complianceblood pressuredisease progression
Publication Date：2017-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 1153-1156 )