Analysis of the influence factors of the clinical effects of extracorporeal membrane oxygenation on severe acute respiratory distress syndrome
Wang Wentao
Qi Shaoyan
Chu Zidong
Chen Chunyan
Zhou Mingkai
Ren Yuxin
LiuXiaojun
Abstract：Objective To summarize the factors of severe acute respiratory distress syndrome (ARDS)patients treated with extracorporeal membrane oxygenation(ECMO).Methods The clinical data of twenty-eight patients with severe ARDS,who met the ECMO criteria,supposed with ECMO in intensive care unit of the Second Affiliated Hospital of Zhengzhou University from August of 2012 to June of 2015 were retrospectively collected and analyzed.Patients were divided into survival group and non-survival group according to the three months situation after ECMO treatment.The statistics software of SPSS 17.0 was used for data analysis.Results 28 patients were treated with VV-ECMO.Mean time of mechanical ventilation before ECMO thera-py was (70.86 ±24.93)h.These factors,such as the age,the time of pre-ECMO mechanical ventilation,the time between paroxysm and ECMO support,were significantly different between the both groups (P<0.05 ),while there was no statistically significant difference in the pathogenesis of ARDS (P>0.05).Those factors,such as the heart rate,the mean arterial pressure, the serum lactate level and the serum procalcitonin level were significantly different between the both groups in the six hours pre-ECMO (P<0.05).Conclusion VV-ECMO may be an effective extracorporeal life support treatment for severe ARDS. These indexes,such as the age,the time of mechanical ventilation before ECMO therapy,the time between paroxysm and ECMO ther-apy,HR,MAP,the serum lactate level and the serum procalcitonin level,may be the risk factors for the patient’s prognosis.
Keywords：extracorporeal membrane oxygenationsevereacute respiratory distress syndromefactors
Publication Date：2016-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 2129-2132 )