Effects of valve operation in patients with valvular heart disease complicated with pulmonary hypertension
Ji Huaxun
Abstract：Objective To observe the therapeutic effects of valve operation (valve replacement or valve forming)in patients with valvular disease and pulmonary hypertension.Methods The clinical data of 60 patients with valvular disease complicated with pulmonary hypertension from January of 2012 to March of 2014 were retrospectively analyzed.The cardiac function and he-modynamics were observed before and after surgery,and the prognosis of patients with different clinical characteristics were ana-lyzed.Results The patients with type Ⅲ and Ⅳ heart function grade before operation had better cardiac function after opera-tion.In 60 patients underwent surgery,2 patients died,the mortality rate was 3%,a total of 20 patients with related complica-tions.The levels of LVEF,MAP,PAP,CI,PVRI and CVP in patients with type Ⅲ and Ⅳ heart function had significant differ-ences between before and after operation.The incidence of complications in patients with combined valvular disease was signifi-cantly higher than patients with single membrane disease,and the higher pulmonary artery pressure,the higher the complication rate (P <0.05),2 patients both died of severe pulmonary hypertension.Conclusion The pulmonary arterial pressure in pa-tients with heart valve disease was highly correlated with the surgical complications,and preoperative pulmonary arterial pressure assessment should be used as a reference index for surgical indications.
Keywords：heart valve diseasepulmonary hypertensionsurgical operationcardiac function
Publication Date：2016-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 797-800 )