Prognostic analysis of non - small cell lung cancer with bone metastasis
Li Mingwei
Kuang Xiankui
Zhao Xiangtong
Huang Kun
Han Wei
Dong Wenjie
Wang Liping
Abstract：Objective To investigate the prognosis - related factors of non - small cell lung cancer(NSCLC)with bone me-tastasis. Methods The clinical data of 78 NSCLC patients with bone metastasis treated in the First Affiliated Hospital of Zheng-zhou University from January of 2013 to June of 2013 were retrospectively analyzed. Kaplan - Meier method was used to estima-tethe 1 - and 2 - year survival rates of patients. Log - rank time series analysis for the univariate analysis was used to screen the factors influencing the survival of patients and Cox proportional hazard model for the multivariate analysis was used to further con-NSCLC were 48. 7% and 15. 4% . Single factor analysis showed that ECOG score,pathological type,other parts of metastasis, chemotherapy and molecular targeted therapy(MTT)were associated with the prognosis of patients(P ﹤ 0. 05). Multivariate a-nalysis showed that ECOG score,pathological type,other parts of metastasis,chemotherapy and molecular targeted therapy were the independent factors of prognosis. Conclusion NSCLC patients with bone metastasis who were with good KPS,adenocarcino-ma,merely bone metastasis,received chemotherapy and MTT had better prognosis.
Keywords：bone metastasisnon - small cell lung cancerprognostic factorssurvival rate
Publication Date：2016-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：4( 601-604 )