Effect of early use of octreotide in cirrhotic patients undergoing splenectomy and devascularization
Hu Hongtao
Tang Zhe
Wan Renrui
Ren Hao
Li Xiangyang
Wu Yang
ZhaoYongfu
Abstract：Objective To investigate the effect of early use of octreotide in cirrhotic patients undergoing splenectomy and de-vascularization.Methods The clinical data of 65 cirrhosis patients with portal hypertension undergoing splenectomy and devas-cularization were retrospectively analyzed.All the patients were divided into observation group (n =29)and control group (n =36)according to whether or not using octreotide after operation.Hemoglobin(Hb),ascites,urine volume on postoperative day (POD)1 ,3,5 and 7 were compared between observation group and control group.Results Compared with control group,the levels of hemoglobin and urine volume on POD 1 ,3,5,7 were significantly increased (P <0.05),and ascites was significantly lower (P <0.05)in observation group.Conclusion The early use of octreotide after splenectomy and devascularization in cir-rhotic patients with portal hypertension can reduce portal vein pressure and the volume of postoperative ascites,also prevent bleed-ing of surgical field.
Keywords：octreotidesplenectomy and devascularizationcirrhosisascites
Publication Date：2016-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：3( 407-409 )