Comparative study of the efficacy and safety of subcutaneous and sublingual immunotherapy for patients with allergic rhinitis
Yu Jiaoyan
Yang Boqiu
Abstract：Objective To investigate the efficacy and safety of subcutaneous and sublingual immunotherapy for patients with allergic rhinitis(AR).Methods 1 56 adult AR patients were randomly divided into subcutaneous specific immunotherapy (sub-cutaneous immunotherapy,SCIT)group (78 cases)and sublingual specific immunotherapy (sublingual immunotherapy,SLIT) group (78 cases )to be treated by standardized dust mite extract.The efficacy and adverse events of both groups were observed and compared.Results After treatment,the nasal symptoms of both groups were improved significantly and the VAS scores were significantly lower than before treatment,and the difference between before and after treatment were statistically significant (P <0.05),but the VAS scores between the two groups after treatment had no statistically significant difference(P >0.05). The total effective rate of SCIT was 89.7% and SLIT group was 84.6%,and the difference was not statistically significant (P >0.05).The adverse reaction rate of SCIT group was 39.7% (31 /78)and SLIT group was 8.9% (7 /78),and the difference was statistically significant (P <0.05).Conclusion Two treatments for AR can achieve good results,but SLIT has a relatively low incidence of adverse reactions.
Keywords：allergic rhinitissubcutaneous immunotherapysublingual immunotherapy
Publication Date：2016-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：3( 220-222 )