A study of the effects of garlic oil on the immune function of mice
Zheng Yu
Zheng Jianfang
Abstract：Objective To study the effects of different doses of garlic oil on the immune function of mice.Methods 1 60 healthy female mice were randomly divided into 4 groups,each group was divided into 4 cages respectively,no.1 ~4,1 0 per cage.No.1 cage in each group was selected as ck,2,3,4 cages were fed with 2.0 mg/kg,4.0 mg/kg,8.0 mg/kg (low,me-dium and high)three doses of garlic oil respectively for 31 d.The viscera/weight ratio was determined in the first 4 cages;car-bon clearance test was carried out in the second batch;the experiments that macrophages in abdominal cavity of mice swallowed up chicken red blood cells was carried out in the third batch;the lymphocyte transformation test was carried out in the fouth batch.Results There was no significant difference in viscera/weight ratio between no.1 cage and no.2 ~4 cages(P >0.05). The phagocytic index in high -dose garlic oil group was significantly higher than the other two groups (P <0.05),and the car-bon clearance ability was improved.The phagocytic ratio of mice eating garlic oil was higher than that in no.1 cage(P <0.05), and with the increase of consumption of dosage,the phagocytic ratio was increased.Optical density difference of mice eating gar-lic oil was higher than that in no.1 cage(P <0.05).Conclusion Garlic oil could improve the immune function of mice.
Keywords：garlic oilcarbon clearance abilitymacrophageslymphocyte transformation test
Publication Date：2016-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：3( 15-17 )