Efficacy of botulinum toxin type A in the treatment of primary intractable trigeminal neuralgia
Fang Li
Hu Chuansong
Ma Yunqing
Teng Junfang
Abstract：Objective To investigate the efficacy of botulinum toxin type A(BTX -A)in the treatment of primary intractable trigeminal neuralgia.Methods 54 patients with primary intractable trigeminal neuralgia were selected and treated with multi -point subcutaneous injection of BTX -A in the painful area and the trigger point.The efficacy was assessed by visual analog scores(VAS)before and 2 weeks,2 month and 6 months after the treatment.Results The VAS before and 2 weeks,2 months and 6 months after the treatment were (10.2 ±1.3),(3.6 ±2.3),(2.8 ±2.2)and(4.8 ±3.1)scores respectively,and the differences were statistically significant(P <0.05).The effective rates at 2 weeks,2 months and 6 months after the treatment were 87.03%、72.22% and 61.11% respectively,and the differences were statistically significant(P <0.05).No severe com-plication was found.Conclusion BTX -A has a significant clinical effect on primary intractable trigeminal neuralgia. <br> and 6 months after the treatment were (10.2 ±1.3),(3.6 ±2.3),(2.8 ±2.2)and(4.8 ±3.1)scores respectively,and the differences were statistically significant(P <0.05).The effective rates at 2 weeks,2 months and 6 months after the treatment were 87.03%、72.22% and 61.11% respectively,and the differences were statistically significant(P <0.05).No severe com-plication was found.Conclusion BTX -A has a significant clinical effect on primary intractable trigeminal neuralgia.
Keywords：primary intractable trigeminal neuralgiabotulinum toxin type Atherapeutic effect
Publication Date：2015-01-01
Online Publishing Date：2026-09-12(First online date of this platform, not the publication date of the document)
Pages：3( 25-27 )